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Symbol
Name
ID
Smo
smoothened, frizzled class receptor
MGI:108075
Phenotype annotations related to endocrine/exocrine glands
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Diabetes mellitus
Exocrine pancreatic insufficiency
Pancreatic adenocarcinoma
Disease(s) Associated with SMO
pancreatic cancer

Mouse Phenotypes
endocrine/exocrine gland phenotype
abnormal pancreas morphology
Availability Mouse Genotype
Gt(ROSA)26Sortm1(Smo/EYFP)Amc/?
Tg(CAG-cre/Esr1*)5Amc/?  (conditional)
Gt(ROSA)26Sortm1(Smo/EYFP)Amc/?
Tg(Pbsn-cre)4Prb/?  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory